Slc gene family
WebThe overview of human SLC superfamily. The human SLC superfamily comprises 386 member proteins that transport a broad spectrum of substrates, such as nutrients, toxins, and prescription drugs. The superfamily members are classified into 52 families, based on the number of predicted or observed transmembrane a-helices (usually 10–14) and ... WebThe solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The SLC superfamily comprises 55 gene families having at least 362 putatively functional protein …
Slc gene family
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WebApr 19, 2024 · Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Front Genet. 2024 Apr 19;13:849789. doi: 10.3389/fgene.2024.849789. eCollection 2024. Authors Di Zheng 1 , Zhun Wei 1 , Weichun … WebApr 10, 2024 · Interaction among variants in the SLC gene family (SLC6A14, SLC26A9, SLC11A1, and SLC9A3) and CFTR mutations with clinical markers of cystic fibrosis - …
WebThe SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety of substances across cellular membranes. While members of this superfamily are found throughout cellular organelles, this review focuses on transporters expressed at the plasma membrane. WebApr 1, 2009 · Many of these transporters belong to the solute-carrier (SLC) gene superfamily, and include passive transporters, sym-porters and antiporters, as well as mitochondrial and vesicular transporters. The SLC superfamily comprises 55 gene families, having at least 362 putatively functional protein-coding genes .
WebApr 19, 2024 · Given the important role of SLC family in essential physiological processes including nutrient uptake, ion transport, and waste removal, and that their dysregulation … WebJan 1, 2009 · The solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The SLC superfamily comprises 55 gene families having at least 362 …
The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the … See more By convention of the nomenclature system, members within an individual SLC family have greater than 20-25% sequence identity to each other. In contrast, the homology between SLC families is very low to non-existent. … See more The following families are named under SLC: 1. high-affinity glutamate and neutral amino acid transporter See more Putative SLCs, also called atypical SLCs, are novel, plausible secondary active or facilitative transporter proteins that share ancestral background with the known SLCs. The atypical … See more Most members of the SLC group are located in the cell membrane, but some members are located in mitochondria (the most notable one being SLC family 25) or other intracellular organelles. See more Names of individual SLC members have the following format: where: • SLC is the root name (SoLute Carrier) • n = an integer representing a family (e.g., 1-52) • X = a single letter (A, B, C, ...) denoting a subfamily See more • Outline of families • Datasets and Reagents on the Solute Carrier Family • List of proteins at HGNC website See more
WebThe SLC (Solute Carrier) series includes the “classical” transporter families (ion-coupled transporters, exchangers, passive transporters, etc.). It contains 65 SLC gene families with 458 different human transporter … orange theory fitness british columbiaWebApr 10, 2024 · Jeffrey D. Allred, Deseret News. Many had seen Sapporo and Salt Lake City as the strongest 2030 bids, suggesting that Sapporo would be chosen to host in 2030 and Salt Lake City in 2034. However, that was before an Olympic scandal surfaced involving the 2024 Summer Games in Tokyo. The impact on public opinion of that scandal, tied to … iphone xr mnp 一括0円WebNov 12, 2008 · We performed a detailed phylogenetic analysis of the entire SLC family and found that 15 of the families place into four large phylogenetic clusters with the largest … iphone xr micro sd cardWebThe SLC8 gene family of sodium-calcium exchangers (NCX) - Structure, function, and regulation in health and disease. Mol Aspects Med. 2013 Apr;34(2-3):220-35. SLC name orange theory fitness gungahlinWebJul 28, 2024 · The solute carrier (SLC) superfamily genes encode more than 300 members that are responsible for the transmembrane transportation of many essential endogenous … iphone xr mockup macbookWebNov 2, 2024 · The human solute carrier ( SLC) superfamily of transporters is comprised of over 400 membrane-bound proteins, and plays essential roles in a multitude of … iphone xr mirror selfieWebSLC16A1: familial hyperinsulinemic hypoglycemia type 7 (FHH7) and symptomatic deficiency in lactate transport (SDLT) The SLC16A1 gene is localized at 1p12 and encodes a proton-linked monocarboxylate transporter 1 (MCT1). The transporter is ubiquitously expressed and transports many monocarboxylates, such as lactate and pyruvate, … orange theory fitness corporate headquarters